Six quarks–up, down, strange, charm, bottom and top–are the building blocks of matter. Protons and neutrons are made of up and down quarks, held together by the strong nuclear force. The DZero experiment has discovered the Cascade-b particle, which contains a down quark (d), strange quark (s) and bottom quark (b). It is the first particle ever observed with one quark from each generation of particles.