Physicists discovered decades ago that odd little particles called neutrinos, of which there are three known “flavors,” morph between these flavors as they travel, and they call this phenomenon neutrino oscillation. The Deep Underground Neutrino Experiment, developed by an international collaboration and hosted by Fermi National Accelerator Laboratory, aims to answer fundamental questions about the early evolution of the universe through its study of these oscillations. This requires a neutrino beam and the ability to sample the neutrinos right out of the gate in their original state and again after they change.
To capture the data, DUNE is building both a near detector and a far detector in the path of the most intense neutrino beam ever created. The hybrid near detector, located only about 2,000 feet downstream from the neutrino source at Fermilab in Batavia, Illinois, will get the first taste. But most of the neutrinos will travel 800 miles on to the far detector at the Sanford Underground Research Facility in Lead, South Dakota, where only a small proportion will interact with the detector because the beam will spread out over that distance and neutrinos are famously elusive. The rest will harmlessly sail on, largely unimpeded, through the Earth’s crust and beyond.
Since the DUNE far detector will use liquid-argon time projection chamber technology to measure neutrinos, it is critical that the same technology be used for the near detector to facilitate a comparison of data on the same target — liquid argon. This part of DUNE’s near detector is called ND-LAr, short for “near detector liquid argon.”
“Despite being only 1% the size of one far detector module, this ND-LAr detector is still large enough to fully contain the signals from neutrinos.”
Michele Weber, the University of Bern
As part of DUNE’s plan to measure neutrinos over a wide range of energies, the ND-LAr, along with an accompanying muon spectrometer, will be able to move sideways off axis to better characterize the beam. A stationary beam monitor will remain on axis to watch for any beam variations that could affect measurements.
“Despite being only 1% the size of one far detector module, this ND-LAr detector is still large enough to fully contain the signals from neutrinos,” said Michele Weber from the University of Bern who is also the leader of the ND-LAr consortium. “This enables a precise comparison with what is seen at the far detector, thereby revealing the neutrino oscillation that occurs between the two sites.”

Given that the neutrino beam broadens with distance, more like the light from a flashlight than a laser beam, the near detector will see a much more concentrated flux of neutrinos than will the far detector — one of the reasons the near detector does not have to be so large. This concentration of neutrinos leads to a phenomenon called “pileup” in the detector, where the rate of neutrino interactions overwhelms the rate at which the detector can record the charge signals that emanate from them. The ND-LAr design cleverly mitigates this problem by segmenting its volume into mini detectors, called modules, with individual pixelated readout. The numerous interactions occur in different modules, without overwhelming any of them.

ND‑LAr uses the novel liquid-argon pixel system, or LArPix, that was invented by physicists and engineers at Lawrence Berkeley National Laboratory. This end‑to‑end pixelated sensor and electronics system can image neutrino events in true 3D, which is an important aspect to resolving individual neutrino interactions in the detector.
Brooke Russell, a researcher with the Massachusetts Institute of Technology, is testing reconstruction efforts for this type of pileup mitigation. By anticipating pileup from the neutrino beam, the team hopes to paint as accurate a picture as possible and not be overwhelmed by the rate of neutrino interactions.
“ND-LAr is unique in that we purposely partition neutrino signals across multiple optically segmented volumes and algorithmically stitch these signals back together,” Russell said.
Through these segmentation and reconstruction efforts, DUNE will provide consistent clarity of the recorded neutrino interactions.
Even with the segmentation, interactions that occur very close to one another in space may be misinterpreted as a single event unless light signals are also collected to separate them in time, according to Zoya Vallari of the Ohio State University, an analysis coordinator for the ND-LAr. The instantaneous signals that scintillation light produces in the liquid argon make it possible to distinguish the potentially overlapping charge signals.
“The prototyping program for the DUNE liquid-argon near detector has been wildly successful, advancing multiple novel detector technologies and algorithms for data analysis.”
Dan Dwyer, Lawrence Berkeley National Laboratory
The DUNE ND-LAr team has been developing and prototyping the segmented liquid-argon time projection chamber design, primarily at the University of Bern, in Switzerland, starting in 2016 with a program called ArgonCube to test the component technologies. In 2022 the steadily growing team constructed and tested a demonstrator of four half-size time-projection chamber modules, called 2×2. After collecting data from a neutrino beam source, this detector is now in a non-beam data collection phase at Fermilab, recording events from cosmic rays and other sources, such as calibration data. The effort currently involves more than 100 scientists from roughly 40 institutions.
“The 2×2 program has been pivotal in shaping our software, simulation and analysis frameworks,” said Vallari. “The data we collected is driving progress in calibration, event reconstruction and charge-light matching.”
“The experience gained with 2×2 has enabled us to thoroughly validate the detector concept in a realistic environment,” added Livio Calivers, a freshly minted Ph.D. from Bern. “As a young researcher, it gave me the opportunity to build an experiment from scratch and ultimately analyze real data from neutrino interactions.”
The team built and tested a single full-scale module in 2024 that incorporated improvements guided by insights from the 2×2 effort. A full row of five modules is currently in the works to test production, assembly and integration procedures, aiming for production to start at Fermilab in 2026.

“The prototyping program for the DUNE liquid-argon near detector has been wildly successful, advancing multiple novel detector technologies and algorithms for data analysis,” said Dan Dwyer of Berkeley Lab who is also the technical lead for ND-LAr. “These results give us confidence that we can cope with the very high intensity of the DUNE neutrino beam and achieve DUNE’s ambitious scientific goals.”
Fermi National Accelerator Laboratory is America’s national laboratory for particle physics and accelerator research. Fermi Forward Discovery Group manages Fermilab for the U.S. Department of Energy Office of Science. Visit Fermilab’s website at www.fnal.gov and follow us on social media.
A collaborative research team comprised of U.S. Department of Energy national laboratories and led by Fermi National Accelerator Laboratory aims to revolutionize custom microelectronics design by using artificial intelligence to accelerate development of chips that can function in extreme environments.
The Accelerating eXtreme Environment Specs-to-Silicon — or AXESS — project will boost innovation and national competitiveness, enabling breakthroughs in quantum computing, fusion energy and particle physics.

AXESS is a collaborative endeavor leveraging the strengths of the vast DOE lab complex — including Oak Ridge National Laboratory, Lawrence Berkeley National Laboratory, SLAC National Accelerator Laboratory and Sandia National Laboratories — as well as university collaborators and leading industry partners such as Siemens.
The team is developing proofs of concept for DOE’s Genesis Mission — a national mission to accelerate science through AI.
Fermilab, America’s particle physics and accelerator laboratory, is well-suited to lead this type of work and extend the adoption of rapid chip design to other research areas.
All of this coming together within the Genesis Mission is a great opportunity for Fermilab to team up with others and use AI to significantly accelerate chip design.”
Nhan Tran, head of Fermilab’s AI Program
“Particle detectors must function in some of the most extreme environments in terms of radiation, cryogenic temperatures and speed,” said Nhan Tran, head of Fermilab’s AI Program. “As a result, we’ve built our own custom detectors for many years, and Fermilab has established deep expertise in microelectronics for extreme environments. More recently, we’ve developed tools and methods used across the community to integrate AI onto chips. All of this coming together within the Genesis Mission is a great opportunity for Fermilab to team up with others and use AI to significantly accelerate chip design.”
Custom-designing specialized chips that are critical to scientific research is a highly iterative, time-intensive process that can take many months — even years — to complete.
Through this proposed Genesis Mission project, the research team is building a framework that uses AI to speed up the chip-design process, dramatically reducing the time from chip specification to fabrication from months to weeks.
“The goal of this framework is to create systems in AI that help designers make the right decisions at each step of the design process, providing feedback for the next set of designers along the pipeline,” said Giuseppe Di Guglielmo, a principal engineer at Fermilab who is co-leading the project.
Traditionally, chips are designed independently in stages, each by a different set of experts. From materials used, transistor and circuit designs, chip architecture, and finally, algorithms that run on the chips, a decision made in one stage might create issues in subsequent stages. Furthermore, the tools used are typically slow and manually operated.

In contrast, researchers on this project are using AI to integrate all stages, ensuring any decision made in one stage optimizes the entire design and opens up traditional bottlenecks. They use one type of AI — large language models — to coordinate and automate manual steps and make high-level decisions, while another type — smaller surrogate models — act as stand-ins for the more complex and time-consuming models.
These surrogate AI models rapidly make predictions, such as how fast the chip will operate, the amount of power it will consume, the performance of the transistors, and so on, through the various stages. Within minutes, they evaluate millions of design options, predict the performance of each and isolate the most promising candidates before sending them through the full design process.
The initial proof of concept is focused on chips used to control quantum sensors, devices and systems. The team has achieved an approximately 500-times speedup for the design phase of the qubit readout algorithm and its implementation as firmware for field-programmable gate arrays. In addition, they have also developed more accurate transistor modeling at 4 kelvin — about minus 450 degrees Fahrenheit — important for operation in quantum environments. Another important area they are studying is radiation-hardened chips for use in high-energy particle physics experiments.
Under the auspices of the Genesis Mission, the researchers hope to expand this effort into a multi-year project.
By uniting Siemens’ proven technologies with the breakthrough science at Fermilab and across the DOE labs, we’re accelerating a new class of chips for quantum, fusion and high-radiation environments — at a speed and scale the nation has never had.”
David Burnette, engineering director at Siemens
“Siemens is putting industrial-grade hardware design solutions behind the Genesis Mission,” said David Burnette, engineering director for Catapult High-Level Synthesis, Siemens Digital Industries Software. “By uniting Siemens’ proven technologies with the breakthrough science at Fermilab and across the DOE labs, we’re accelerating a new class of chips for quantum, fusion and high-radiation environments — at a speed and scale the nation has never had.”
“We are really excited to be able to partner with other DOE labs and industries that have strong and complementary capabilities, bringing all these experts together across microelectronics and AI to make a big push forward for national success,” said Tran.
Fermi National Accelerator Laboratory is America’s national laboratory for particle physics and accelerator research. Fermi Forward Discovery Group manages Fermilab for the U.S. Department of Energy Office of Science. Visit Fermilab’s website at www.fnal.gov and follow us on social media
Fermi National Accelerator Laboratory and the Sanford Underground Research Facility held an event today in Lead, S.D., celebrating a significant milestone for the most ambitious neutrino research experiment in the United States, the Deep Underground Neutrino Experiment at the Long-Baseline Neutrino Facility. The event commemorated the start of 10 million pounds of steel beams being moved a mile underground to build the structural elements that will form DUNE’s detector elements.
“Today represents the start of a pivotal phase for DUNE, the development of the far detector structures in South Dakota,” Fermilab Director Norbert Holtkamp said. “As we advance this historic effort, our focus remains on safety, quality and schedule — in that order — to ensure we successfully deliver on behalf of the U.S. Department of Energy, our nation and the world.”
Holtkamp added, “We at Fermilab are grateful for the support from DOE and the close collaboration of our science partners at SURF, CERN and the many international institutions that are contributing to DUNE.”

CERN, the European Organization for Nuclear Research, provided personnel, expertise and an in-kind contribution of 10 million pounds of steel for the detectors being assembled underground in South Dakota. This is the first time CERN has invested in infrastructure for an experiment outside of Europe.
The steel cryostat materials contributed by CERN for DUNE are scheduled to be moved underground and prepared for installation this summer. This marks an important transition from construction to detector installation and demonstrates the tangible impact of international in-kind contributions to DUNE.
“This important milestone for DUNE is a testament to the strong scientific partnership between CERN and the United States,” said CERN Director General Mark Thomson. “CERN is playing a pivotal role in the development of its prototype detectors and providing the two enormous cryostats for the experiment itself, while the U.S. Department of Energy national laboratories likewise are playing a critical role for CERN with state-of-the-art superconducting accelerator magnets for the High-Luminosity Large Hadron Collider.”

As America’s particle physics laboratory, Fermilab is host to DUNE — a world-leading, flagship experiment that is the largest scientific project supported by the DOE Office of Science and the largest in the United States. The project will study the neutrino, one of the universe’s most abundant yet least understood subatomic particles. DUNE will send the world’s most intense neutrino beam a distance of 800 miles from Fermilab in Illinois to detectors deep underground at SURF, enabling it to explore fundamental questions about the nature of matter, the evolution of the universe and the origin of matter-antimatter asymmetry.
In addition to expanding our fundamental knowledge, neutrino research has the vast potential to drive advances across a range of fields, including national security, communications and medical imaging.
“DUNE is a powerful example of DOE’s commitment to advancing American leadership in science,” said DOE Under Secretary for Science Darío Gil, one of the attendees at today’s event. “On behalf of the entire DOE leadership team, I offer my congratulations to Fermilab and all those involved in this historic initiative, including our partners around the world who helped make this milestone possible.”
Today’s event provided attendees the opportunity to sign one of the steel beams that will be installed underground for DUNE’s first detector module, including a cryostat that will be used to cool thousands of tons of liquid argon to about minus 300 degrees Fahrenheit to capture neutrino interactions with unprecedented precision. Each of the two planned modules will be roughly the size of a five-story building, measuring 216 feet long, 62 feet wide and 60 feet high. Once complete, the two cryostats will each house 17,000 tons of liquid argon nearly a mile underground at SURF.

Mike Headley, the executive director of the South Dakota Science and Technology Authority and laboratory director at SURF, attributes the success of this project to the international collaboration behind this world-class research.
“SURF is proud to be included among the 1,500 scientific collaborators from around the world who are working alongside hundreds of additional engineers and technicians to complete this project,” Headley said. “We’re excited to see the delivery of this steel a mile underground and to assist in the construction of this colossal experiment.”
With the start of the installation of the underground detectors, Fermilab’s priority is to deliver the first neutrino beam to DUNE by 2031.
Fermi National Accelerator Laboratory is America’s national laboratory for particle physics and accelerator research. Fermi Forward Discovery Group manages Fermilab for the U.S. Department of Energy Office of Science. Visit Fermilab’s website at www.fnal.gov and follow us on social media.
The DOE Office of Science is the single largest supporter of basic research in the physical sciences in the United States and is working to address some of the most pressing challenges of our time. For more information, please visit science.energy.gov.
About SURF:
Sanford Underground Research Facility is operated by the South Dakota Science and Technology Authority (SDSTA) with funding from the Department of Energy’s Office of Science. We are America’s Underground Lab. Our mission is to advance world-class science and inspire learning across generations. For more information, please visit www.sanfordlab.org.
About CERN:
CERN, the European Organization for Nuclear Research, is one of the world’s leading laboratories for particle physics. The Organization is located on the French-Swiss border, with its headquarters in Geneva. Its Member States are: Austria, Belgium, Bulgaria, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Israel, Italy, Netherlands, Norway, Poland, Portugal, Romania, Serbia, Slovakia, Slovenia, Spain, Sweden, Switzerland and the United Kingdom. Cyprus is an Associate Member State in the pre-stage to Membership. Brazil, Chile, Croatia, India, Ireland, Latvia, Lithuania, Pakistan, Türkiye, and Ukraine are Associate Member States. Japan and the United States of America currently have Observer status, as do the European Union and UNESCO. The Observer status of JINR is suspended in accordance with the CERN Council Resolution of 25 March 2022. For more information, please visit home.cern.
Anna Grassellino, chief technology officer and associate laboratory director for the Technology Directorate at Fermi National Accelerator Laboratory, has been appointed to the U.S. Department of Energy’s Office of Science Advisory Committee, known as SCAC — a federal advisory body that provides independent advice on scientific priorities and strategies.
Grassellino will also serve as chair of the SCAC quantum subcommittee. In that role, she will help guide national efforts toward DOE’s 2028 goal for error-corrected quantum computers capable of addressing major scientific challenges. The subcommittee is also charged with exploring partnership opportunities and leveraging resources across the broad U.S. quantum ecosystem. These can include unique capabilities at national labs, innovations emerging in the private sector and resources across other federal agencies.
SCAC provides guidance to the DOE Office of Science on major scientific and technical issues, including emerging opportunities and cross-cutting initiatives. The quantum subcommittee will assess the current state of quantum information science and identify the key steps needed to advance the field at the national level.
“Anna brings a combination of scientific excellence, technical vision and leadership in large-scale quantum initiatives,” Fermilab Director Norbert Holtkamp said. “We congratulate Anna on this very important appointment and will fully support the committees and her work.”

Grassellino is an internationally recognized physicist and director of the DOE’s Superconducting Quantum Materials and Systems Center, a national quantum information science research center led by Fermilab. Her work has advanced superconducting technologies for both accelerators and quantum systems, including innovations that have enabled record performance and new capabilities in superconducting devices. “I am honored to serve on SCAC and to chair the quantum subcommittee,” Grassellino said. “This is an important opportunity to help define a clear path forward for quantum information science and to accelerate progress toward fault-tolerant quantum computing.”
Fermi National Accelerator Laboratory is America’s national laboratory for particle physics and accelerator research. Fermi Forward Discovery Group manages Fermilab for the U.S. Department of Energy Office of Science. Visit Fermilab’s website at www.fnal.gov and follow us on social media.
The Superconducting Quantum Materials and Systems Center is one of the five U.S. Department of Energy National Quantum Information Science Research Centers. Led by Fermi National Accelerator Laboratory, SQMS is a collaboration of more than 40 partner institutions — national labs, academia and industry — working together to bring transformational advances in the field of quantum information science. The center leverages Fermilab’s expertise in building complex particle accelerators to engineer multiqubit quantum processor platforms based on state-of-the-art qubits and superconducting technologies. Working hand in hand with embedded industry partners, SQMS will build a quantum computer and new quantum sensors at Fermilab, which will open unprecedented computational opportunities. For more information, please visit sqmscenter.fnal.gov.